In Press
Lee, Y., Muddaluru, V., Anwar, S., Wilson J.Y., and Campos, A.R.* A screen of kinase inhibitors revelas a potential role of Chk1 in regulating Hydra head regeneration and maintenance. In Press with International Journal of Developmental Biology.
Manzon, L.A.1, Zak, M.A.1, Agee, M., Boreham, D.R., Wilson, J.Y., Somers, C.M., Manzon, R.G.* Thermal acclimation alters both basal heat shock protein gene expression and the heat shock response in juvenile lake whitefish (Coregonus clupeaformis). In Press with Journal of Thermal Biology. 1co-first authors
2021
Sessions KJ, Whitehouse, LM, Manzon, L.A., Boreham, D.R., Wilson, J.Y., Somers C.M., and Manzon, R.G.* 2021. The heat shock response shows plasticity in embryonic lake whitefish (Coregonus clupeaformis) exposed to repeated thermal stress. Journal of Thermal Biology, 100:103036.
Nemec-Bakk A, Niccoli S, Davidson C, Roy D, Stoa L, Sreetharan S, Simard A, Boreham D, Wilson J, Tai TC, Lees SJ, Khaper N*. 2021. Lasting effects of low to non-lethal radiation exposure during late gestation on offspring’s cardiac metabolism and oxidative stress. Antioxidants 10:816.
Harman, AA, Fuzzen, M, Stoa, L, Boreham, D, Manzon R, Somers CM, Wilson, JY*. 2021. Evaluating tank acclimation and trial length for shuttle box temperature preference assays. Journal of Experimental Biology 224:jeb233205. Pre-print in BioRxiv.
Pankov, KV, McArthur, AG, Gold, AG, Nelson, DR, Goldstone, JV, and Wilson JY. * 2021. The cytochrome P450 (CYP) superfamily in cnidarians. Scientific Reports 11:9834.
Restivo,VR, Kidd KK, Surette MG, Bucking, C, and Wilson JY* . 2021. The gut content microbiome of wild-caught rainbow darter is altered during laboratory acclimation. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 39:100835.
Thome,C*, Mitz, C, Thompson, J, Cybulski, ME, Somers, CM, Manzon, RG, Wilson, JY, Boreham, DR. 2021. A model to predict embryonic development and hatching in lake whitefish (Coregonus clupeaformis) under variable incubation temperatures. Journal of Great Lakes Research, 47:494-503.
McEvoy, J*; Jones, D; Stoa, L; Dixon, DL; Tai, TC; Hooker, AM; Boreham, DR; Wilson, JY. 2021. Unchanged cardiovascular and respiratory outcomes in healthy C57Bl/6 mice after in utero exposure to low dose ionizing radiation. International Journal of Radiation Biology, 97: 131-138.
Lee, A.H., Fraz, S., Purohit, U., Campos A.R., Alsop, D. and Wilson, J.Y.* 2021. Chronic exposure of brown (Hydra oligactis) and green (Hydra viridissima) hydra to environmentally relevant concentrations of pharmaceuticals. Science of the Total Environment 732:139232.
Restivo, VR, Kidd KK*, Surette MG, Servos, MR, and Wilson JY. 2021. Rainbow darter (Etheostoma caeruleum) exposed to wastewater effluent in the field have altered gut microbiomes. Science of the Total Environment 751:141724
2020
Galus, M., Fraz, S., Gugilla, A., Jönsson, M., and Wilson, J.Y. 2020. Prostaglandins prevent acetaminophen induced embryo toxicity in zebrafish (Danio rerio). Environmental Toxicology and Pharmacology 80:103463.
Thome, C.*, Laframboise, T., Mitz, C., Clancy, E., Bates, J., Somers, C.M., Manzon, R.G., Wilson, J.Y., Gunn, J.M., and Boreham, D.R. 2020. Modifying effects of a cobble substrate on thermal environments and implications for embryonic development in lake whitefish (Coregonus clupeaformis). Journal of Fish Biology 97:113-120.
Harris, J.B., Hartman, J.H., Luz, A.L., Wilson, J.Y., Dinyari, A., and Meyer, J.* 2020. Zebrafish CYP1A expression in Caenorhabditis elegans protects from exposure to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture. Toxicology 440:1-11.
Adrian-Kalchhauser I, Blomberg A, Solbakken MH, Larsson T, Musilova Z, Peart CR, Pippel M, Suurväli J, Walser JC, Wilson JY, Rosenblad MA, Burguera D, Gutnik S, Michiels N, Tölpel M, Pankov K, Schloissnig S, Winkler S. 2020. The round goby genome provides insights into mechanisms that may facilitate biological invasions. BMC Biology 18:11; bioRxiv doi:https://doi.org/10.1101/708974
Graham, C.F., Boreham, D.R., Manzon, R.G., Stott, W., Wilson, J.Y., and Somers C.M.. 2020. How “simple” methodological decisions affect interpretation of popoulation structure based on reduced representation library DNA sequencing: a case study using the lake whitefish. PLOS One 15:e0226608.
2019
Fraz, S., Lee, A.H, Pollard, S., Srinivasan, K., Vermani, A., David, E., and Wilson, J.Y.* 2019. Paternal exposure to carbamazepine impacts zebrafish offspring reproduction over multiple generations. Environmental Science and Technology 53:12734-12743.
Mitz, C.*, Thome, C., Cybulski, M.E., Somers, C.M., Manzon, R.G., Wilson, J.Y., and Boreham, D.R. 2019. Thermal dependence of size-at-hatch in the lake whitefish (Coregonus clupeaformis). Canadian Journal of Fisheries and Aquatic Sciences 76:2069-2079.
Sreetharan, S., Stoa, L., Cybulski, M.E., Jones, DE., Lee, AH., Kulesza, AV., Tharmalingam, S, Boreham, DR, Tai, TC and Wilson, JY*. 2019. Cardiovascular and Growth Outcomes of C57Bl Mice Offspring Exposed to Maternal Stress and Ionizing Radiation During Pregnancy. International Journal of Radiation Biology 95:1085-1093.
Fraz, S., Lee, A.H, Pollard, S., Srinivasan, K, Vermani, A., and Wilson, J.Y.* 2019. Parental gemfibrozil exposure impacts zebrafish F1 offspring, but not subsequent generations. Aquatic Toxicology 212:194-204.
Alsop, D.E.* and Wilson, J.Y. 2019. Waterborne pharmaceutical uptake and toxicity is modified by pH an dissolved organic carbon in zebrafish. Aquatic Toxicology, 210:11-18.
Shaya, L., Jones, D., and Wilson, J.Y.* 2019. CYP3C gene regulation by the aryl hydrocarbon and estrogen receptors in zebrafish. Toxicology and Applied Pharmacology, 362:77-85.
2018
Eme, J.*, Mueller, C.A., Lee, A.H., Melendez,C., Manzon, R.G., Somers, C.M., Boreham, D.R., and Wilson, J.Y. 2018. Daily, repeating fluctuations in embryonic incubation temperature alter metabolism and growth of Lake whitefish (Coregonus clupeaformis). Journal of Comparative Physiology B, 226:49-56.
Lim, M., Manzon, R.G., Somers, C.M., Boreham, D.R., and Wilson, J.Y*. 2018. Impacts of temperature, morpholine, and chronic radiation on the embryonic development of round whitefish (Prosopium cylindraceum). Environmental Toxicology and Chemistry, 37:2593-2608.
Hulley, E.N., Taylor, N.D.J., Zarnke, A.M., Somers, C.M., Mazon, R,G., Wilson, J.Y., and Boreham, D.R.* 2018. DNA barcoding vs. morphological identification of larval fish and eggs in Lake Huron: advantages to a molecular approach. Journal of Great Lakes Research 44: 1110-1116.
Choi, E., Alsop, D, and Wilson, J.Y.* 2018. The effects of chronic acetaminophen exposure on the kidney, gill, and liver in rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology 198:20-29.
2018
Morgan, T.D.; Graham, C.F.; McArthur, A.G.; Raphenya, A.R.; Boreham, D.R.; Manzon, R.G.;Wilson, J.Y.,Lance, S.L.; Howland, K.L.; Patrick, P.H.; Somers, C.M. 2018. Genetic population structure of the round whitefish (Prosopium cylindraceum) in North America: multiple markers reveal glacial refugia and regional subdivision. Canadian Journal of Fisheries and Aquatic Sciences, 75:836-849.
Fraz, S., Lee, A.H.,and Wilson J.Y. 2018. Gemfibrozil and carbamazepine decrease steroid production in zebrafish testes (Danio rerio). Aquatic Toxicology, 198:1-9.
Hammill, K.M., Fraz, S., Lee, A.H., and Wilson, J.Y. 2018. The effects of parental carbamazepine exposure on sexual differentiation in zebrafish (Danio rerio). Environmental Toxicology and Chemistry, 37:1696-1706.
Sreetharan, S., Thome, C., Tsang, K.K.;Somers, C.M.; Manzon, R.G.; Boreham, D.R.; Wilson, J.Y. 2018. Micronuclei formation in rainbow trout cells exposed to multiple stressors: morpholine, heat shock, and ionizing radiation. Toxicology In Vitro 47:38-47.
2017
Lim, M.Y.T., Manzon, R.G., Somers, C.M., Boreham, D.R., and Wilson, J.Y. 2017. The effects of fluctuating temperature regimes on the embryonic development of lake whitefish (Coregonus clupeaformis). Comparative Biochemistry and Physiology A Molecular and Integrative Physiology, 214:19-29.
Thome, C,Mitz, C, Manzon, R, Somers, C, Wilson, JY and Boreham, D. 2017 Initial Characterization of the growth stimulation and heat shock induced adaptive response in developing lake whitefish embryos after ionizing radiation. Radiation Research188:475-485.
Mitz, C, Thome, C,Manzon, R, Somers, C, Wilson, JY and Boreham, D 2017 Is there a trade-off between radiation stimulated growth and metabolic efficiency? Radiation Research188:486-494.
Whitehouse, L.M., McDougall, C.S., Stefanovic, D.I., Boreham, D.R., Somers, C.M., Wilson J.Y., and Manzon, R.G. 2017. Development of the embryonic heat shock response and the impact of repeated thermal stress in early stage lake whitefish (Coregonus clupeaformis) embryos. Journal of Thermal Biology 69:294-301.
Mueller, C.A., Doyle, L., Eme, J.,Manzon, R.G, Somers, C.M,Boreham, D.R., and Wilson, J.Y. 2017. Lipid content and fatty acid profile during development of lake whitefish (Coregonus clupeaformis) embryos at different incubation temperatures. Comparative Biochemistry and Physiology A Molecular and Integrative Physiology 203:201-209.
Mitz, C, Thome, C,Thompson, J, Manzon, R, Somers, C, Wilson, JY1and Boreham, D1 2017. A method to transform a variable thermal regime to an equivalent constant temperature. Journal of Thermal Biology 65:21-25. 1equal contributors
Thome, C,Mitz, C,, Sreetharan, S., Mitz, C., Somers, C, Manzon, R, Boreham, D., and Wilson, JY. 2017. Developmental effects of the industrial cooling water additives morpholine and sodium hypochlorite on lake whitefish (Coregonus clupeaformis).Environmental Toxicology and Chemistry, 36:1955-1965.
Verbueken, E, Alsop, D.,Saad, M.A., Pype, C., Van Peer, E.M., Casteleyn, C.R., Van Ginneken, C.J, Wilson, J.Y.,and Van Cruchten, S.J. 2017 In Vitro Biotransformation of Two Human CYP3A Probe Substrates and its Inhibition during Early Zebrafish Development. International Journal of Molecular Sciences19: E217.
Sreetharan, S.; Thome, C.; Tharmalingam, S.; Jones, D.E.; Kulesza, A.Y.; Wilson, J.Y., Boreham, D.R.; Tai, T.C. 2017 Ionizing Radiation Exposure During Pregnancy: Effects on Postnatal Development and Life. Radiation Research187:647-658.
Eberts, R.L., Wissel, B., Simpson, G.L., Crawford, S.S., Stott, W., Hanner, R.H., Manzon, R.G., Wilson, J.Y., Boreham, D.R., and Somers, C.M 2017. Isotopic structure of Lake Whitefish in Lake Huron: evidence for regional and local populations based on resource use. North American Journal of Fisheries Management 37:133-148.
2016
Eberts, R.L., Wissel, B., Manzon, R.G., Wilson, J.Y., Boreham, D.R., and Somers, C.M. 2016. Consistent differential resource use by sympatric Lake (Coregonus clupeaformis) and Round (Prosopium cylindraceum) Whitefish in Lake Huron: a multi-time scale isotopic niche analysis. Canadian Journal of Fisheries and Aquatic Sciences73:1072-1080.
Thome, C., Mitz, C.,Somers, C.M.,Manzon, R.G.,Boreham, D.R., Wilson, J.Y..2016. Incubation of Lake Whitefish (Coregonus clupeaformis) embryos in cooling water discharge and the impacts of fluctuating thermal regimes on development. Canadian Journal of Fisheries and Aquatic Sciences73:1213-1221.
Hanwell D, Hutchinson S, Collymore C, Bruce A.E.,Louis R, Ghalami A, Allison W.T., Ekker M, Eames, B.F., Childs, S, Kurrasch, D.M., Gerlai, R, Thiele, T, Scott I, Ciruna, B, Dowling J, McFarlane S, Huang P, Wen X, Drapeau P, Babiuk L.A., Dragon D., Smida A, Buret A.G., O’Grady E., Wilson J, Sowden-Plunkett L,and Tropepe , V. 2016. Restrictions on the importation of zebrafish into Canada associated with spring viremia of carp virus. Zebrafish 13 Suppl 1:S153-163.
Lee, A.H., Eme, J., Mueller,C.A.,Manzon, R.G., Somers, C.M., Boreham,D.R., Wilson, J.Y.. 2016. The effects of increased constant incubation temperature and cumulative acute heat shock exposures on morphology and survival of Lake Whitefish (Coregonus clupeaformis) embryos. Journal of Thermal Biology 57:11-20.
Graham CF, Eberts RL, Morgan TD, Boreham DR, Lance SL, Manzon RG, Martino, J.A., Rogers, S.M., Wilson, JY.,and Somers, C.M. 2016 Fine-Scale Ecological and Genetic Population Structure of Two Whitefish (Coregoninae) Species in the Vicinity of Industrial Thermal Emissions. PLoS ONE11(1): e0146656.
Stefanovic, D.I., Manzon, L.A., Boreham, D.R., Somers, C.M., Wilson, J.Y., Manzon, R.G. 2016. Thermal Stress and the Heat Shock Response in Embryonic and Young of the Year Juvenile Lake Whitefish. Comparative Biochemistry and Physiology A, 193:1-10.
2015
Graham, C., Glenn,T.C., McArthur, A., Boreham, D.R., Kieran, T., Lance, S. Manzon, R., Martino, J.A., Pierson, T.,Rogers, S.M., Wilson, J. and Somers, C.M. 2015. Impacts of degraded DNA on Restriction Enzyme Associated DNA Sequencing (RADSeq). Molecular Ecology Resources, 15:1304-1315.
Sreetharan, S., Thome, C., Mitz, C. Eme, J., Meuller, C, Hulley, E., Manzon, R.G., Somers, C.M., Boreham, D., and Wilson, J.Y. 2015. Embryonic development of lake whitefish (Coregonus clupeaformis): a staging series, analysis of growth and impacts of fixation. Journal of Fish Biology 87:539-558.
Mueller, C.A., Eme, J., Boreham, D., Manzon, R.G., Somers, C.M., and Wilson, J.Y. 2015. Embryonic Critical Windows: Changes in incubation temperature alter survival, hatchling phenotype, and cost of development in Lake whitefish (Coregonus clupeaformis) embryos. Journal of Comparative Physiology B, 185:315-331.
Eme, J., Mueller, C.A., Manzon, R., Somers, C.M., Boreham, D.R. and Wilson, J.Y. 2015.Critical windows in embryonic development: Shifting incubation temeraptures alter heart rate and oxygen consumption of Lake Whitefish (Coreogonus clupeaformis) embryos and hatchlings. Comparative Biochemstry and Phsyiology Part A Molecular and Integrative Physiology 179:71-80.
2014
Dejong, C. and Wilson, J.Y 2014. The cytochrome P450 superfamily complement (CYPome) in the annelid Capitella telata. PlosONE, 9:e107728.
Shaya, L, Dejong, C, and Wilson, J.Y. 2014.Expression patterns of cytochrome P450 3B and 3C genes in model fish species. Comparative Biochemistry and Physiology Part C Toxicology and Pharmacology 165:115-125.
Mitz, C, Thome, C, Cybulski, ME, LaFramboise, L, Wilson, JY1 and Boreham, D1. 2014. Small-scale rearing of Lake Whitefish (Coreogoneus clupeaformis) embryos for experimental aquaculture. North American Journal of Aquaculture 76:179-184. 1 equal contributors
Galus, M, Rangaranjan, S., Lai, A., Shaya, L., Balshine,S. and Wilson, J.Y. 2014. Effects of chronic, parental pharmaceutical exposure on zebrafish (Danio rerio) offspring. Aquatic Toxicology, 151:124-134.
2013
Galus, M., Kirischian, N., Higgins, S., Purdy, J., Chow, J., Ragaranjan, S., Li, H., Metcalfe, C., and Wilson, J.Y. 2013. Chronic, low concentration exposure to pharmaceuticals impacts mulitple organ systems in zebrafish. Aquatic Toxicology,132-133:200-211 .
Galus, M., Jeyaranjaan, J., Smith, E.M., Li, H, Metcalfe, C., and Wilson, J.Y. 2013. Chronic Effects of Exposure to a Pharmaceutical Mixture and Municipal Wastewater in Zebrafish. Aquatic Toxicology, 132-133:212-222.
2012
Smith, E.S., Iftikar, F.I., Higgins, S., Irshad, S., Jandoc, R., Lee, M., and Wilson, J.Y. 2012. In vitro inhibition of cytorchrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes. Aquatic Toxicology, 109:259-266.
2011
Harskamp, J., Britz-McKibbin, P., and Wilson, J.Y. 2011. Functional Screening of Cytochrome P450 Activity and Uncoupling by Capillary Electrophoresis. Analytical Chemistry, 84: 862–866.
Kirischian, N.L. and Wilson, J.Y. 2011. Phylogenetic and functional analyses of the cytochrome P450 family 4. Molecular Phylogenetics and Evolution, 62:458-471.
Kirischian, N., McArthur A.G., Jesuthasan C., Krattenmacher B., and Wilson J.Y. 2011. Phylogenetic and Functional Analysis of the Vertebrate Cytochrome P450 2 Family. Journal of Molecular Evolution, 72:56-71.
2010
Scornaienchi, M.L., Thornton, C., Willett, K.L., Wilson, J.Y. 2010. Cytochrome P450 mediated 17-beta estradiol metabolism in zebrafish (Danio rerio). Journal of Endocrinology, 206:317-325.
Marentette, J.R., Gooderham,K.L., Hynes, H., McMaster, M.E., Ng, T., Parrott, J.L., Slater, G.F., Wilson, J.Y., Wood, C.M., and Balshine, S. 2010. Signatures of Contamination in Invasive Round Gobies (Neogobius melanostomus): A double strike for ecosystem health in highly polluted areas? Journal of Ecotoxicology and Environmental Safety, 73:1755-1764.
Scornaienchi, M.L., Thornton, C., Willett, K.L., Wilson, J.Y. 2010. Functional differences in the cytochrome P450 1 family enzymes from Zebrafish (Danio rerio) using heterologously expressed proteins. Archive of Biochemistry and Biophysics, 502:17-22.
Bowley, L.A., Alam, F., Marentette, J.R., Balshine, S., Wilson, J.Y. 2010. Characterization of vitellogenin gene expression in round goby (Neogobius melanostomus) using a quantitative PCR assay. Environmental Toxicology and Chemistry, 29:2751-2760.
Smith, E.M. and Wilson, J.Y. 2010. Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16α-carbonitrile, rifampicin, and β-naphthoflavone. Aquatic Toxicology 97:324-333.
Smith, E.M., Chu, S., Paterson, G., Metcalfe, C.D. and Wilson J.Y. 2010. Cross species comparison of fluoxetine metabolism with fish liver microsomes. Chemosphere 79:26-32.
Wilson, J.Y. and Stegeman J.J. 2010. Catalytic and Immunochemical Detection of Hepatic and Extrahepatic Microsomal Cytochrome P450 1A1 (CYP1A1) in White-sided Dolphin (Lagenorhynchus acutus) Aquatic Toxicology 96:216-224.
2009
Noori, A., Selvaganapathy, P.R., and Wilson, J. 2009. Microinjection in a microfluidic format using flexible and compliant channels and electroosmotic dosage control. Lab on a Chip 9: 3202:3211.
2008
Hooker, S.K., Metcalfe, T.L., Metcalfe, C.D., Angell, C.M., Wilson, J.Y., Moore, M.J., and Whitehead, H. 2008. Changes in persistent contaminant load and CYP1A1 enzyme activity in biopsy samples from Northern bottlenose whales, Hyperoodon ampullatus, following the onset of nearby oil and gas activity. Environmental Pollution, 152 (1): 205-216.
2007
Wilson, J.Y., Wells, R. Aguiliar, A., Borrell, A., Tornero, V., Reijnders, P., Moore, M., and Stegeman, J.J. 2007. Corrrelates of cytochrome P450 1A1(CYP1A1) expression in bottlenose dolphin (Tursiops truncatus) integument biopsies. Toxicological Sciences, 97(1):111-119.
2006
Garrick, R.A., Woodin, B.R., Wilson, J.Y., Middlebrooks, B.L., and Stegeman, J.J. 2006. Cytochrome P4501A is induced in endothelial cell lines from the kidney and lung of the bottlenose dolphin, Tursiops truncatus. Aquatic Toxicology, 76(3-4):295-305.
2005
Wilson, J.Y., Cooke,S.R., Moore, M.J., Martineau, D., Mikaelian, I., Metner, D.A., Lockhart, W.L., and Stegeman, J.J. 2005. Systemic Effects of Arctic Pollutants in Beluga whales Indicated by CYP1A1 expression. Environmental Health Perspectives, 113(11):1594-1599.
Wilson, J.Y., McArthur, A.G., and Stegeman, J.J. 2005. Characterization of a Cetacean Aromatase (CYP19) and the Phylogeny and Functional Conservation of Vertebrate Aromatase. General and Comparative Endocrinology, 140:74-83.
2004
Angell, C.M., Wilson, J.Y., Moore, M.J. and Stegeman, J.J. 2004 Cytochrome P450 1A1 expression in cetacean integument: implications for detecting contaminant exposure and effects. Marine Mammal Science 20(3):554-566.
Godard, C., Smolowitz, R., Wilson, J.Y., Payne, R., Stegeman, J.J. 2004. Induction of cetacean cytochrome P4501A1 by B-naphthoflavone exposure of skin biopsy slices. Toxicological Sciences 80:268-275.
2001
Wilson, JY; Kruzynski, GM; Addison, RF. 2001. Experimental exposure of juvenile chinook (Oncorhynchus tshawytscha) to bleached kraft mill effluent: hepatic CYP1A induction is correlated with DNA adducts but not with organochlorine residues. Aquatic Toxicology, 53(1):49-63.
2000
Wilson, J.Y., Addison, R.F., Martens, D., Gordon, R. and Glickman, B. 2000. Cytochrome P450 1A and related measurements in juvenile chinook (Oncorhynchus tshawytscha) from the Fraser River. Canadian Journal of Fisheries and Aquatic Sciences, 57(2):405-413.
1996
Hodson, P.V., Efler, S., Wilson, J.Y., El-Shaarawi, A., Maj, M. and Williams, T.G. 1996. Measuring the Potency of Pulp Mill Effluents for Induction of Hepatic Mixed Function Oxygenase Activity in Fish. Journal of Toxicology and Environmental Health, 49(1):83:110.
1993
LaPierre, N., Wilson, J., Bourreau, J.P., Tougas, G., Kwan, C.Y., Daniel, E.E. 1993. Norepinephrine Release in Rat Vas Deferens – Effect of Rauwolscine and BHT-920. Life Sciences, 53(2): PL19-PL24.